Software for Statistical Folding of Nucleic Acids and Studies of Regulatory RNAs

Thursday May 30, 2024

Sribo 3656 sequences folded since April 1, 2003
Job mode
Email address for batch job submission
Please enter a name for your sequence
Please choose your input format

Please enter the sequence to be folded.
Note: for all input formats, characters other than A, T, C, G, U or N in the sequence will be edited out.

or click on Browse button to upload your sequence file

Please check if you need to reverse the sequence and then take its complement for folding
Length of Helix III (including first 2 base pairs of the triplet)
Preferred cleavage triplet for hammerhead ribozyme for energy calculation
Length of Helix I
Additional constraint information (optional)

P  i  0  k to force bases i,i+1,...,i+k-1 to be single stranded

P  i  j  k to prevent consecutive base pairs (i,j),(i+1,j-1),...,(i+k-1,j-k+1) to form
Folding temperature 37°C
Ionic conditions 1M NaCl, no divalent ions

fold 2.2
- Ding RNA Bioinformatics Lab